Flunarizine allows differentiation between mechanisms of arrhythmias in the intact heart.

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Flunarizine allows differentiation between mechanisms of arrhythmias in the intact heart.

The calcium antagonist flunarizine suppresses pathologic accumulation of calcium intracellularly without affecting the fast sodium or the slow calcium channel. To establish its value in differentiating between mechanisms of arrhythmias in the canine heart, the effect of flunarizine was investigated on ventricular tachycardia (VT) induced by ouabain intoxication or occurring 16-24 hours after oc...

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ژورنال

عنوان ژورنال: Circulation

سال: 1990

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.81.1.343